Article
Use of gene-expression profiling to identify prognostic subclasses in adult acute myeloid leukemia.
The New England journal of medicine - 15 Apr 2004
Bullinger Lars, Döhner Konstanze, Bair Eric, Fröhling Stefan, Schlenk Richard F, Tibshirani Robert, Döhner Hartmut, Pollack Jonathan R
Abstract excerpt
BACKGROUND: In patients with acute myeloid leukemia (AML), the presence or absence of recurrent cytogenetic aberrations is used to identify the appropriate therapy. However, the current classification system does not fully reflect the molecular heterogeneity of the disease, and treatment stratifi...
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