Article
Somatic Mutations and the Risk of Undifferentiated Autoinflammatory Disease in MDS: An Under-Recognized but Prognostically Important Complication.
Frontiers in immunology - 1 Jan 2021
Watad Abdulla, Kacar Mark, Bragazzi Nicola Luigi, Zhou Qiao, Jassam Miriam, Taylor Jan, Roman Eve, Smith Alexandra, Jones Richard A, Amital Howard, Cargo Catherine, McGonagle Dennis, Savic Sinisa
Abstract excerpt
Objectives: We theorized that myelodysplastic syndrome (MDS) with somatic mutations and karyotype abnormalities are associated with autoinflammation, and that the presence of autoinflammatory disease affected prognosis in MDS. Methods: One hundred thirty-four MDS patients were assessed for the prevalence of autoinflammatory complications and its link with karyotypes and somatic mutation status. Autoinflammatory...
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