Article
[Value of immunohistochemical staining with mutation-specific antibodies in detecting EGFR mutations: a meta-analysis].
Zhongguo fei ai za zhi = Chinese journal of lung cancer - 20 Jun 2014
Ma Qing, Wang Jing, Zhong Diansheng, Ning Chao, Liu Chang, Xiao Ping
Abstract excerpt
BACKGROUND: It has been proven that epidermal growth factor receptor (EGFR) mutation is the most important predictive factor for determining the effect of EGFR tyrosine kinase inhibitors (TKIs) applied to non-small cell lung cancer (NSCLC) patients. The patients with EGFR mutations response better to TKIs. To detect EGFR mutation has been particularly essential to select first-line treatment for lung cancer...
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