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Article

Immunohistochemistry for EGFR Mutation Detection in Non-Small-Cell Lung Cancer.

Clinical lung cancer - 1 May 2017

Hitij Nina Turnšek, Kern Izidor, Sadikov Aleksander, Knez Lea, Stanič Karmen, Zwitter Matjaž, Cufer Tanja

Abstract excerpt

INTRODUCTION: The sensitivity and specificity of immunohistochemistry (IHC) was compared with the standard polymerase chain reaction (PCR)-based method for detecting common activating epidermal growth factor receptor (EGFR) mutations in non-small-cell lung cancer (NSCLC). Additionally, we evaluated predictive value of IHC EGFR mutation-positive status for EGFR tyrosine kinase inhibitor (TKI) treatment outcome and...

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Identifiers

PMID: 28089159
DOI: 10.1016/j.cllc.2016.11.021

Genes

EGFR

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