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Article

Long-term phlebotomy successfully alleviated hepatic iron accumulation in a ferroportin disease patient with a mutation in SLC40A1: a case report.

BMC gastroenterology - 5 Mar 2021

Nishina Sohji, Tomiyama Yasuyuki, Ikuta Katsuya, Tatsumi Yasuaki, Toki Yasumichi, Kato Ayako, Kato Koichi, Yoshioka Naoko, Sasaki Kyo, Hara Yuichi, Hino Keisuke

Abstract excerpt

BACKGROUND: Hereditary hemochromatosis is a heterogenous group of inherited iron-overload conditions that is characterized by increased intestinal absorption and deposition in vital organs. Hepcidin is a soluble regulator that acts to attenuate both intestinal iron absorption and iron release from reticuloendothelial macrophages through internalization of ferroportin-1, an iron exporter. Ferroportin disease is...

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Identifiers

PMID: 33673803
DOI: 10.1186/s12876-021-01674-z
PMCID: PMC7934381

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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