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Article

Iron chelators reverse organ damage in type 4B hereditary hemochromatosis: Case reports.

Medicine - 2 Apr 2021

Wu Ling-Yan, Song Zhen-Ya, Li Qing-Hai, Mou Li-Jun, Yu Ying-Ying, Shen Si-Si, Song Xiao-Xiao

Abstract excerpt

RATIONALE: Hereditary hemochromatosis (HH) is a hereditary disorder of iron metabolism. It is classified into 4 main types depending on the underlying genetic mutation: human hemochromatosis protein (HFE) (type 1), hemojuvelin (HJV) (type 2A), HAMP (type 2B), transferrin receptor-2 (TFER2) (type 3), and ferroportin (type 4). Type 4 HH is divided into 2 subtypes according to different mutations: type 4A (classical...

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Identifiers

PMID: 33787609
DOI: 10.1097/MD.0000000000025258
PMCID: PMC8021318

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