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Article

Liver biopsies from human females contain male hepatocytes in the absence of transplantation.

Laboratory investigation; a journal of technical methods and pathology - 1 Dec 2004

Stevens Anne M, McDonnell W Michael, Mullarkey Meghan E, Pang Jennifer M, Leisenring Wendy, Nelson J Lee

Abstract excerpt

Fetal cells derived from pregnancy can persist in a woman's blood and tissues for decades and have been implicated in the pathogenesis of autoimmune disease. Transplantation studies based on donor sex mismatch suggest that circulating stem cells can lead to liver regeneration with donor-derived hepatocytes. However, male cells in female liver could derive from pregnancy. We investigated male cells in liver...

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PMID: 15502859
DOI: 10.1038/labinvest.3700193

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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