The 72-kilodalton protein of the male reproductive tract is differentially expressed and developmentally regulated during Wolffian duct differentiation of the fetal mouse.

Abstract excerpt

Differentiation of the mammalian reproductive tract into the male phenotype is dependent on the presence of functional testes secreting testosterone during in utero development. Recently, we identified a protein fraction (72 kDa) from the developing reproductive tract of the fetal male mouse that is able to mimic the effect of testosterone in stabilizing the Wolffian duct in vitro, suggesting a role played by...

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