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Article

Role of PTEN, PI3K, and mTOR in Triple-Negative Breast Cancer

17 Nov 2021

Abstract excerpt

Breast cancer is the most commonly occurring malignancy and the leading cause of cancer-related death in women. Triple-negative breast cancer (TNBC) is the most aggressive subtype and is associated with high recurrence rates, high incidence of distant metastases, and poor overall survival. The aim of this study was to investigate the PI3K/PTEN/Akt/mTOR pathway as one of the most frequently deregulated pathways in...

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PMID: 34833123
DOI: 10.3390/life11111247

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