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Spontaneous and Engineered Large Animal Models of Neurofibromatosis Type 1

16 Feb 2021

Abstract excerpt

Animal models are crucial to understanding human disease biology and developing new therapies. By far the most common animal used to investigate prevailing questions about human disease is the mouse. Mouse models are powerful tools for research as their small size, limited lifespan, and defined genetic background allow researchers to easily manipulate their genome and maintain large numbers of animals in general...

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PMID: 33669386
DOI: 10.3390/ijms22041954

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