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Population Bottlenecks and Intra-host Evolution During Human-to-Human Transmission of SARS-CoV-2

15 Feb 2021

Abstract excerpt

The emergence of the novel human coronavirus, SARS-CoV-2, causes a global COVID-19 (coronavirus disease 2019) pandemic. Here, we have characterized and compared viral populations of SARS-CoV-2 among COVID-19 patients within and across households. Our work showed an active viral replication activity in the human respiratory tract and the co-existence of genetically distinct viruses within the same host. The...

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PMID: 33659260
DOI: 10.3389/fmed.2021.585358

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