Article
Concomitant KIAA1549-BRAF fusion and IDH mutation in Pediatric spinal cord astrocytoma: a case report and literature review.
Brain tumor pathology - 1 Apr 2021
Sun Mengxue, Wang Leiming, Lu Dehong, Zhao Zhilian, Teng Lianghong, Wang Weimin, Piao Yueshan
Abstract excerpt
Primary tumors of the spinal cord are rare, accounting for 3-6% of tumors in the central nervous system, particularly in children. KIAA1549-BRAF fusion is more common in pilocytic astrocytoma (PA) and IDH1 R132H mutation is rare in infratentorial tumors. Here, we report a 10-year-old male patient who presented with weakness in lower limbs that progressed to difficulty walking. Magnetic resonance imaging (MRI)...
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