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Article

Systemic Options for Malignant Peripheral Nerve Sheath Tumors.

Current treatment options in oncology - 27 Feb 2021

Hassan Ayesha, Pestana Roberto Carmagnani, Parkes Amanda

Abstract excerpt

OPINION STATEMENT: Malignant peripheral nerve sheath tumors (MPNSTs) are rare mesenchymal neoplasms that represent a profound therapeutic challenge due to their high proclivity for recurrence and metastasis and relatively poor response to systemic therapy regimens. While our understanding of the pathophysiology of MPNST is growing, including loss of the tumor suppressor gene neurofibromin and subsequent...

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Identifiers

PMID: 33641042
DOI: 10.1007/s11864-021-00830-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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