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Epidemiology of molecular probes in Xpert MTB/RIF assay in Khyber Pakhtunkhwa, Pakistan.

Archives of microbiology - 1 Jul 2021

Khan Anwar Sheed, Khan Muhammad Tahir, Ali Sajid, Khan Taj Ali, Qasim Muhammad, Malik Arif, Ali Sajid, Sajjad Wasim, Ain Qurrat Ul, Irfan Muhammad

Abstract excerpt

Regardless of a plethora of advanced diagnostics, TB and drug resistance remains a principal killer. We proposed gold nanoparticles (AuNPs) attached with probes to enhance the efficiency of GeneXpert MTB/RIF assay instead of conventional dye probes for molecular detection. A total of 15,000 samples were collected from TB suspects and subjected to Xpert MTB/RIF assay, where 6800 (45.3%) were detected as MTB...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 33640990
DOI: 10.1007/s00203-021-02242-5

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