Article
Methylenetetrahydrofolate reductase gene polymorphism, global DNA methylation and blood pressure: a population based study from North India.
BMC medical genomics - 27 Feb 2021
Yadav Suniti, Longkumer Imnameren, Joshi Shipra, Saraswathy Kallur Nava
Abstract excerpt
BACKGROUND: Hypertension is a complex disorder affected by gene-environment interactions. Methylenetetrahydrofolate reductase (MTHFR) gene is one of the genes in One Carbon Metabolic (OCM) pathway that affects both blood pressure and epigenetic phenomenon. MTHFR C677T gene polymorphism leads to r...
Topics
- Humans
- Methylenetetrahydrofolate Reductase (NADPH2)
- DNA Methylation
- India
- Middle Aged
- Male
- Female
- Adult
- Blood Pressure
- Hypertension
- Aged
- Cross-Sectional Studies
- Case-Control Studies
- Polymorphism, Single Nucleotide
- Antihypertensive Agents