ASAP1 promotes tumor progression and angiogenesis and independently predicts poor prognosis and lymph node metastasis of gastric cancer

Abstract excerpt

<title>Abstract</title> <p>Background: Although ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 1(ASAP1) is involved in the development of various malignancies, its clinical significance and mechanism in gastric cancer (GC) remains unclear. <h4>Methods:</h4> The effects of ASAP1 on tumor progression, angiogenesis, and epithelial-mesenchymal transition were evaluated in vitro. The effects of ASAP1 on tumor gr...

Topics

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• Caveolin-1 and cellular processes
• Cell Adhesion Molecules Research
• Cell Cycle
• Cell Proliferation
• Epithelial-Mesenchymal Transition
• Peptidase Inhibition and Analysis
• Signaling Pathways in Disease
• Stomach Neoplasms

Identifiers and source

Literature Corpus work

7329d85b-c5e1-51a1-9e78-81f408820b5c

DOI

10.21203/rs.2.17932/v2