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ATP5B promotes the metastasis and growth of gastric cancer by activating the FAK/AKT/MMP2 pathway

14 Mar 2021

Abstract excerpt

Adenosine triphosphate (ATP) in the tumor microenvironment serves a vital role during tumor progression. ATP synthase F1 β subunit (ATP5B) is one of the most important subunits of ATP synthase and increases cellular ATP levels. ATP5B reportedly participates in carcinogenesis in several tumors. However, the regulatory mechanisms of ATP5B remain poorly understood in gastric cancer (GC). Here, we determined that...

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PMID: 33715234
DOI: 10.1096/fj.202000608r

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