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Article

Silencing ARAF Suppresses the Malignant Phenotypes of Gallbladder Cancer Cells.

BioMed research international - 1 Jan 2020

Lin Weiguo, Tong Chenhao, Zhang Weiguang, Cen Wenda, Wang Yali, Li Jiandong, Zhu Zhiyang, Yu Jianhua, Lu Baochun

Abstract excerpt

ARAF is a member of the RAF kinase family that is necessary for mitogen-activated protein kinase (MAPK) activation in various malignancies, including lung, colorectal, pancreatic, and breast cancers. As the most common biliary tract tumor, gallbladder cancer (GBC) seriously harms human health while the function of ARAF in GBC remains elusive. Here, we found that ARAF expression was upregulated in gallbladder...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32923479
DOI: 10.1155/2020/3235786
PMCID: PMC7453270

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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