Common Genetic Variation in Humans Impacts In Vitro Susceptibility to SARS-CoV-2 Infection.

doi:10.1016/j.stemcr.2021.02.010

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Common Genetic Variation in Humans Impacts In Vitro Susceptibility to SARS-CoV-2 Infection.

Stem cell reports - 9 Mar 2021

Dobrindt Kristina, Hoagland Daisy A, Seah Carina, Kassim Bibi, O'Shea Callan P, Murphy Aleta, Iskhakova Marina, Fernando Michael B, Powell Samuel K, Deans P J Michael, Javidfar Ben, Peter Cyril, Møller Rasmus, Uhl Skyler A, Garcia Meilin Fernandez, Kimura Masaki, Iwasawa Kentaro, Crary John F, Kotton Darrell N, Takebe Takanori, Huckins Laura M, tenOever Benjamin R, Akbarian Schahram, Brennand Kristen J

Abstract excerpt

The host response to SARS-CoV-2, the etiologic agent of the COVID-19 pandemic, demonstrates significant interindividual variability. In addition to showing more disease in males, the elderly, and individuals with underlying comorbidities, SARS-CoV-2 can seemingly afflict healthy individuals with profound clinical complications. We hypothesize that, in addition to viral load and host antibody repertoire, host...

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Identifiers

PMID: 33636110
DOI: 10.1016/j.stemcr.2021.02.010
PMCID: PMC7881728

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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