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Article

Statistical power in COVID-19 case-control host genomic study design.

Genome medicine - 28 Dec 2020

Lin Yu-Chung, Brooks Jennifer D, Bull Shelley B, Gagnon France, Greenwood Celia M T, Hung Rayjean J, Lawless Jerald, Paterson Andrew D, Sun Lei, Strug Lisa J

Abstract excerpt

The identification of genetic variation that directly impacts infection susceptibility to SARS-CoV-2 and disease severity of COVID-19 is an important step towards risk stratification, personalized treatment plans, therapeutic, and vaccine development and deployment. Given the importance of study design in infectious disease genetic epidemiology, we use simulation and draw on current estimates of exposure,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 33371892
DOI: 10.1186/s13073-020-00818-2
PMCID: PMC7768597

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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