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Article

An emerging role for cellular crosstalk in the cancer stem cell niche

26 Feb 2021

Abstract excerpt

Although cumulative genetic and epigenetic changes in cancer cells are correlated with tumor malignancy, accumulating evidence supports that tumor cell-extrinsic mechanisms play an essential role in driving tumor progression. The tissue architecture surrounding tumor cells evolves during disease progression and becomes a significant barrier to cancer treatments. The functional traits of the tumor microenvironment...

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PMID: 33634866
DOI: 10.1002/path.5655

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