Article
Evolutionary conservation of the DRACH signatures of potential N6-methyladenosine (m6A) sites among influenza A viruses.
Scientific reports - 25 Feb 2021
Bayoumi Mahmoud, Munir Muhammad
Abstract excerpt
The addition of a methyl group to the N6-position of adenosine (m6A) is considered one of the most prevalent internal post-transcriptional modifications and is attributed to virus replication and cell biology. Viral epitranscriptome sequencing analysis has revealed that hemagglutinin (HA) mRNA of H1N1 carry eight m6A sites which are primarily enriched in 5'-DRACH-3' sequence motif. Herein, a large-scale...
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