Article
Combining Osimertinib With Chemotherapy in EGFR-Mutant NSCLC at Progression.
Clinical lung cancer - 1 May 2021
White Maya N, Piotrowska Zofia, Stirling Kevin, Liu Stephen V, Banwait Mandeep K, Cunanan Kristen, Sequist Lecia V, Wakelee Heather A, Hausrath Daniel, Neal Joel W
Abstract excerpt
BACKGROUND: Osimertinib is a third-generation EGFR tyrosine kinase inhibitor that has improved survival and central nervous system (CNS) outcomes in patients with non-small cell lung cancer (NSCLC) with activating EGFR mutations. However, little is known about the efficacy and safety of combining osimertinib with chemotherapy. METHODS: This was a retrospective study performed at 3 institutions. Patients with...
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