Article
An overview of osimertinib as a treatment of non-small cell lung cancer (NSCLC): an update.
Expert opinion on pharmacotherapy - 1 May 2021
Cerbone Luigi, Benitez Jose Carlos, Planchard David, Genova Carlo
Abstract excerpt
Introduction: Osimertinib is a third-generation anti-epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI), that irreversibly binds to mutant EGFR, specifically to the T790M EGFR mutant non-small cell lung cancer (NSCLC). Since its approval, osimertinib has been tested in multiple scenarios, including the first-line and adjuvant setting of EGFR-mutant disease.Areas covered: The authors summarize...
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