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Article

Osimertinib: A Review in Previously Untreated, EGFR Mutation-Positive, Advanced NSCLC.

Targeted oncology - 1 Sept 2021

Lamb Yvette N

Abstract excerpt

Activating mutations in the epidermal growth factor receptor (EGFR) gene have been identified as key oncogenic drivers of non-small cell lung cancer (NSCLC). Osimertinib (Tagrisso®) is an orally administered, third-generation EGFR tyrosine kinase inhibitor (EGFR-TKI) that is widely approved for the first-line treatment of advanced NSCLC with activating EGFR mutations. In the pivotal phase III FLAURA trial,...

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Identifiers

PMID: 34564820
DOI: 10.1007/s11523-021-00839-w
PMCID: PMC8536603

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