Combined Analysis of Concordance between Liquid and Tumor Tissue Biopsies for RAS Mutations in Colorectal Cancer with a Single Metastasis Site: The METABEAM Study.

doi:10.1158/1078-0432.CCR-20-3677

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Article

Combined Analysis of Concordance between Liquid and Tumor Tissue Biopsies for RAS Mutations in Colorectal Cancer with a Single Metastasis Site: The METABEAM Study.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 May 2021

Kagawa Yoshinori, Elez Elena, García-Foncillas Jesús, Bando Hideaki, Taniguchi Hiroya, Vivancos Ana, Akagi Kiwamu, García Ariadna, Denda Tadamichi, Ros Javier, Nishina Tomohiro, Baraibar Iosune, Komatsu Yoshito, Ciardiello Davide, Oki Eiji, Kudo Toshihiro, Kato Takeshi, Yamanaka Takeharu, Tabernero Josep, Yoshino Takayuki

Abstract excerpt

PURPOSE: OncoBEAM™ is a circulating tumor DNA (ctDNA) test that uses the BEAMing digital PCR technology. We clarified the association between the baseline tumor burden and discordance in the RAS status by metastatic sites in patients with a single metastatic site. EXPERIMENTAL DESIGN: Data from previous Spanish and Japanese studies investigating the concordance of the RAS status between OncoBEAM™ and tissue...

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PMID: 33602686
DOI: 10.1158/1078-0432.CCR-20-3677

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