Article
Blood-based RAS mutation testing: concordance with tissue-based RAS testing and mutational changes on progression.
Future oncology (London, England) - 1 Oct 2020
Germetaki Theodora, Nicholls Camille, Adams Richard A, Braun Michael, Rogan Jane, Moghadam Sharzad, Lenfert Eva, Lukas Antje, Edelstein Daniel L, Jones Frederick S, Saunders Mark P
Abstract excerpt
Aim: To determine the concordance between plasma and tissue RAS mutation status in metastatic colorectal cancer patients to gauge whether blood-based testing is a viable alternative. We also evaluated the change in mutation status on progression. Materials/methods: RAS testing was performed on plasma from patients commencing first-line therapy (OncoBEAM™ RAS CEIVD kit). Results were then compared with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.