Article
Cell‐specific network analysis of human folliculogenesis reveals network rewiring in antral stage oocytes
18 Feb 2021
Abstract excerpt
Although previous studies have explored the gene expression profiles of human oocytes and granulosa cells by single-cell RNA sequencing (scRNA-seq), the dynamic regulatory network at a single-cell resolution during folliculogenesis remains largely unknown. We identified 10 functional modules by WGCNA, four of which were significantly correlated with primary/antral oocyte and antral/pre-ovulatory granulosa cells....
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