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Article

Targeting oncogenic mutations in colorectal cancer using cryptotanshinone.

PloS one - 1 Jan 2021

Vundavilli Haswanth, Datta Aniruddha, Sima Chao, Hua Jianping, Lopes Rosana, Bittner Michael

Abstract excerpt

Colorectal cancer (CRC) is one of the most prevalent types of cancer in the world and ranks second in cancer deaths in the US. Despite the recent improvements in screening and treatment, the number of deaths associated with CRC is still very significant. The complexities involved in CRC therapy stem from multiple oncogenic mutations and crosstalk between abnormal pathways. This calls for using advanced molecular...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33596259
DOI: 10.1371/journal.pone.0247190
PMCID: PMC7888617

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