Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Systems Pharmacology-Based Discovery of Natural Products for Precision Oncology Through Targeting Cancer Mutated Genes.

CPT: pharmacometrics & systems pharmacology - 1 Mar 2017

Fang J, Cai C, Wang Q, Lin P, Zhao Z, Cheng F

Abstract excerpt

Massive cancer genomics data have facilitated the rapid revolution of a novel oncology drug discovery paradigm through targeting clinically relevant driver genes or mutations for the development of precision oncology. Natural products with polypharmacological profiles have been demonstrated as promising agents for the development of novel cancer therapies. In this study, we developed an integrated systems...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Products
Share to Clinical Trials as Topic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Databases, Factual

Share to Drug Discovery

Share to Medicine, Chinese Traditional

Share to Molecular Targeted Therapy

Share to Neoplasms

Share to Precision Medicine

Source

Open in PubMed Open full text

Identifiers

PMID: 28294568
DOI: 10.1002/psp4.12172
PMCID: PMC5356618

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Systems Pharmacology-Based Discovery of Natural Products for Precision Oncology Through Targeting Cancer Mutated Genes.PMID 28294568Read ↗

In silico polypharmacology of natural productsSemantic proximity Read ↗

A network-based drug repositioning infrastructure for precision cancer medicine through targeting significantly mutated genes in the human cancer genomes.Semantic proximity Read ↗

Quantitative and Systems Pharmacology 3. Network-Based Identification of New Targets for Natural Products Enables Potential Uses in Aging-Associated DisordersSemantic proximity Read ↗

Review of Personalized Medicine and Pharmacogenomics of Anti-Cancer Compounds and Natural Products.Semantic proximity Read ↗

Pharmacogenomics in Practice: Why Traditional Medicine Still LeadsSemantic proximity Read ↗

Review of Personalized Medicine and Pharmacogenomics of Anti-Cancer Compounds and Natural ProductsSemantic proximity Read ↗

DBPOM: a comprehensive database of pharmaco-omics for cancer precision medicineSemantic proximity Read ↗

A Co-essentiality Network of Cancer Driver Genes Better Prioritizes Anticancer DrugsSemantic proximity Read ↗

A systems pharmacology approach to determine the mechanisms of action of pleiotropic natural products in breast cancer from transcriptome dataSemantic proximity Read ↗

A brief survey on computational approaches to reveal drug and disease associations.Semantic proximity Read ↗

Targeting Oncogenic Mutations in Colorectal Cancer using CryptotanshinoneSemantic proximity Read ↗

Integrative Statistical Inferences for Drug Sensitivity Biomarkers in CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.