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Article

Next Generation Imaging Techniques to Define Immune Topographies in Solid Tumors.

Frontiers in immunology - 1 Jan 2020

Pietrobon Violena, Cesano Alessandra, Marincola Francesco, Kather Jakob Nikolas

Abstract excerpt

In recent years, cancer immunotherapy experienced remarkable developments and it is nowadays considered a promising therapeutic frontier against many types of cancer, especially hematological malignancies. However, in most types of solid tumors, immunotherapy efficacy is modest, partly because of the limited accessibility of lymphocytes to the tumor core. This immune exclusion is mediated by a variety of...

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Identifiers

PMID: 33584676
DOI: 10.3389/fimmu.2020.604967
PMCID: PMC7873485

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