Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Ultra high-risk PFA ependymoma is characterized by loss of chromosome 6q

9 Feb 2021

Abstract excerpt

BACKGROUND: Within PF-EPN-A, 1q gain is a marker of poor prognosis, however, it is unclear if within PF-EPN-A additional cytogenetic events exist which can refine risk stratification. METHODS: Five independent non-overlapping cohorts of PF-EPN-A were analyzed applying genome-wide methylation arrays for chromosomal and clinical variables predictive of survival. RESULTS: Across all cohorts, 663 PF-EPN-A were...

Source

Identifiers

PMID: 33580238
DOI: 10.1093/neuonc/noab034

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ultra high-risk PFA ependymoma is characterized by loss of chromosome 6qPMID 33580238Read ↗

Significant increase of high-risk chromosome 1q gain and 6q loss at recurrence in posterior fossa group A ependymoma: A multicenter studySemantic proximity Read ↗

Clinically relevant molecular hallmarks of PFA ependymomas display intratumoral heterogeneity and correlate with tumor morphologySemantic proximity Read ↗

Molecular Staging of Intracranial Ependymoma in Children and AdultsSemantic proximity Read ↗

Genomic Amplifications and Distal 6q Loss: Novel Markers for Poor Survival in High-risk Neuroblastoma Patients.Semantic proximity Read ↗

Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumorsSemantic proximity Read ↗

Molecular heterogeneity and CXorf67 alterations in posterior fossa group A (PFA) ependymomas.Semantic proximity Read ↗

Significance of molecular classification of ependymomas: C11orf95-RELA fusion-negative supratentorial ependymomas are a heterogeneous group of tumorsSemantic proximity Read ↗

Comprehensive profiling of myxopapillary ependymomas identifies a distinct molecular subtype with relapsing diseaseSemantic proximity Read ↗

Molecular subtyping of ependymoma and prognostic impact of Ki-67Semantic proximity Read ↗

Chromosome 1q gain and tenascin-C expression are candidate markers to define different risk groups in pediatric posterior fossa ependymoma.Semantic proximity Read ↗

Transcriptomic and epigenetic dissection of spinal ependymoma (SP-EPN) identifies clinically relevant subtypes enriched for tumors with and without NF2 mutation.Semantic proximity Read ↗

Genetic abnormalities detected in ependymomas by comparative genomic hybridisationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.