Article
Chromosome 1q gain and tenascin-C expression are candidate markers to define different risk groups in pediatric posterior fossa ependymoma.
Acta neuropathologica communications - 22 Aug 2016
Araki Asuka, Chocholous Monika, Gojo Johannes, Dorfer Christian, Czech Thomas, Heinzl Harald, Dieckmann Karin, Ambros Inge M, Ambros Peter F, Slavc Irene, Haberler Christine
Abstract excerpt
Intracranial classic (WHO grade II) and anaplastic (WHO grade III) ependymomas are among the most common tumors in pediatric patients and have due to frequent recurrences and late relapses a relatively poor outcome. The impact of histopathological grading on patient outcome is controversial and therefore, molecular prognostic and predictive markers are needed to improve patient outcome. To date, the most...
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