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Article

Genetic Variants of ANGPT1, CD39, FGF2 and MMP9 Linked to Clinical Outcome of Bevacizumab Plus Chemotherapy for Metastatic Colorectal Cancer.

International journal of molecular sciences - 30 Jan 2021

Gaibar María, Galán Miguel, Romero-Lorca Alicia, Antón Beatriz, Malón Diego, Moreno Amalia, Fernández-Santander Ana, Novillo Apolonia

Abstract excerpt

Angiogenesis pathway genes show substantial genetic variability causing inter-individual differences in responses to anti-angiogenic drugs. We examined 20 single nucleotide polymorphisms (SNPs) in 13 of these genes to predict tumour response and clinical outcome measured as progression free survival (PFS) and overall survival (OS) in 57 patients with metastatic colorectal cancer (mCRC) given bevacizumab plus...

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Identifiers

PMID: 33573134
DOI: 10.3390/ijms22031381
PMCID: PMC7866547

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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