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Article

Velo-cardio-facial syndrome: a model for understanding the genetics and pathogenesis of schizophrenia

1 Nov 2001

Abstract excerpt

BACKGROUND: Individuals with velocardio-facial syndrome (VCFS), a genetic disorder associated with microdeletions of chromosome 22q11, are reported to have high rates of psychiatric disorder, particularly schizophrenia. AIMS: To review the evidence for an association between VCFS and schizophrenia: to outline recent neuropsychological, neuroanatomical and genetic studies of individuals with VCFS; and to make...

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PMID: 11689394
DOI: 10.1192/bjp.179.5.397

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