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Article

The role of FOXL2, SOX9, and β-catenin expression and DICER1 mutation in differentiating sex cord tumor with annular tubules from other sex cord tumors of the ovary.

Virchows Archiv : an international journal of pathology - 1 Aug 2021

Onder Semen, Hurdogan Ozge, Bayram Aysel, Yilmaz Ismail, Sozen Hamdullah, Yavuz Ekrem

Abstract excerpt

Sex cord tumor with annular tubules (SCTAT) is a highly rare type of ovarian sex cord-stromal tumor (SCST), the diagnosis of which remains to be challenging. The aim of this study was to scrutinize the utility of three immunohistochemical markers including Forkhead box protein 2 (FOXL2), SOX9, and β-catenin and DICER1 mutation status in distinguishing SCTATs from other ovarian SCSTs. Nine cases of SCTAT, 10...

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PMID: 33566167
DOI: 10.1007/s00428-021-03052-2

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