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Article

Interferons and other cytokines, genetics and beyond in COVID-19 and autoimmunity.

Cytokine & growth factor reviews - 1 Apr 2021

Opdenakker Ghislain, Van Damme Jo

Abstract excerpt

Interferons are the best antiviral agents in vitro against SARS-CoV-2 so far and genetic defects in their signaling cascade or neutralization of alfa-interferons by autoantibodies come with more severe COVID-19. However, there is more, as the SARS-CoV-2 dysregulates not only innate immune mechanisms but also T and B cell repertoires. Most genetic, hematological and immunological studies in COVID-19 are at present...

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Identifiers

PMID: 33563543
DOI: 10.1016/j.cytogfr.2021.01.004
PMCID: PMC7845543

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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