Article
Insights from the reanalysis of high-throughput chemical genomics data for Escherichia coli K-12.
G3 (Bethesda, Md.) - 18 Jan 2021
Wu Peter I-Fan, Ross Curtis, Siegele Deborah A, Hu James C
Abstract excerpt
Despite the demonstrated success of genome-wide genetic screens and chemical genomics studies at predicting functions for genes of unknown function or predicting new functions for well-characterized genes, their potential to provide insights into gene function has not been fully explored. We systematically reanalyzed a published high-throughput phenotypic dataset for the model Gram-negative bacterium Escherichia...
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