Article
Broad spectrum mutational analysis of chromophobe renal cell carcinoma using next-generation sequencing.
Pathology, research and practice - 1 Mar 2021
Mollica Veronica, Franceschini Tania, Gruppioni Elisa, Rizzo Alessandro, Ricci Costantino, Schiavina Riccardo, Brunocilla Eugenio, Ardizzoni Andrea, Fiorentino Michelangelo, Giunchi Francesca, Massari Francesco
Abstract excerpt
BACKGROUND: Chromophobe renal cell carcinoma (ChRCC) is a rare subtype of non-clear cell renal cell carcinoma. Due to its rarity, its molecular characterization as well as therapeutic targets are still not fully understood. METHODS: We performed a next-generation sequencing analysis using the platform Ion PGM System on 20 retrospectively collected ChRCC cases with the aim of identify molecular biomarkers with...
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