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Article

Genomic and metabolic characterization of a chromophobe renal cell carcinoma cell line model (UOK276)

24 Jul 2017

Abstract excerpt

Chromophobe renal cell carcinoma (ChRCC) represents 5% of all RCC cases and frequently demonstrates multiple chromosomal losses and an indolent pattern of local growth, but can demonstrate aggressive features and resistance to treatment in a metastatic setting. Cell line models are an important tool for the investigation of tumor biology and therapeutic drug efficacy. Currently, there are few ChRCC-derived cell...

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PMID: 28736828
DOI: 10.1002/gcc.22476

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