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A Naturally Heteroplasmic Clam Provides Clues about the Effects of Genetic Bottleneck on Paternal mtDNA.

Genome biology and evolution - 1 Mar 2021

Iannello Mariangela, Bettinazzi Stefano, Breton Sophie, Ghiselli Fabrizio, Milani Liliana

Abstract excerpt

Mitochondrial DNA (mtDNA) is present in multiple copies within an organism. Since these copies are not identical, a single individual carries a heterogeneous population of mtDNAs, a condition known as heteroplasmy. Several factors play a role in the dynamics of the within-organism mtDNA population: among them, genetic bottlenecks, selection, and strictly maternal inheritance are known to shape the levels of...

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Identifiers

PMID: 33555290
DOI: 10.1093/gbe/evab022
PMCID: PMC7936021

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