Article
Structure, transcription, and variability of metazoan mitochondrial genome: perspectives from an unusual mitochondrial inheritance system.
Genome biology and evolution - 1 Jan 2013
Ghiselli Fabrizio, Milani Liliana, Guerra Davide, Chang Peter L, Breton Sophie, Nuzhdin Sergey V, Passamonti Marco
Abstract excerpt
Despite its functional conservation, the mitochondrial genome (mtDNA) presents strikingly different features among eukaryotes, such as size, rearrangements, and amount of intergenic regions. Nonadaptive processes such as random genetic drift and mutation rate play a fundamental role in shaping mtDNA: the mitochondrial bottleneck and the number of germ line replications are critical factors, and different patterns...
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