Article
NLRC5/CITA expression correlates with efficient response to checkpoint blockade immunotherapy.
Scientific reports - 5 Feb 2021
Yoshihama Sayuri, Cho Steven X, Yeung Jason, Pan Xuedong, Lizee Gregory, Konganti Kranti, Johnson Valen E, Kobayashi Koichi S
Abstract excerpt
Checkpoint blockade-mediated immunotherapy is emerging as an effective treatment modality for multiple cancer types. However, cancer cells frequently evade the immune system, compromising the effectiveness of immunotherapy. It is crucial to develop screening methods to identify the patients who would most benefit from these therapies because of the risk of the side effects and the high cost of treatment. Here we...
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