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Article

Bivariate genome-wide association study (GWAS) of body mass index and blood pressure phenotypes in northern Chinese twins.

PloS one - 1 Jan 2021

Li Zhaoying, Wang Weijing, Tian Xiaocao, Duan Haiping, Xu Chunsheng, Zhang Dongfeng

Abstract excerpt

Recently, new loci related to body mass index (BMI) or blood pressure (BP) have been identified respectively in genome-wide association studies (GWAS). However, limited studies focused on jointly associated genetic variance between systolic pressure (SBP), diastolic pressure (DBP) and BMI. Therefore, a bivariate twin study was performed to explore the genetic variants associated with BMI-SBP, BMI-DBP and SBP-DBP....

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Identifiers

PMID: 33539483
DOI: 10.1371/journal.pone.0246436
PMCID: PMC7861438

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