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Article

Effect of -55C/T Polymorphism of Uncoupling Protein 3 Gene on Risk for New-Onset Diabetes in Chinese Peritoneal Dialysis Patients: A Prospective Cohort Study.

Blood purification - 1 Jan 2021

Chen Yun, Dai Shuqi, Shang Da, Ge Xiaolin, Xie Qionghong, Hao Chuan-Ming, Zhu Tongying

Abstract excerpt

BACKGROUND: A high-glucose load in therapy can cause new-onset diabetes (NOD) in peritoneal dialysis (PD) patients. Genetic variability may result in risk modulation. OBJECTIVES: This study aims to investigate the association between -55C/T polymorphism of uncoupling protein 3 (UCP3) gene and the risk of NOD in PD patients. METHODS: Nondiabetic incident PD patients between May 2005 and January 2017 were recruited...

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PMID: 33535204
DOI: 10.1159/000513151

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