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Article

Variations in Orf3a protein of SARS-CoV-2 alter its structure and function

27 Jan 2021

Abstract excerpt

Severe acquired respiratory syndrome coronavirus 2 (SARS-CoV-2) rapidly spread worldwide and acquired multiple mutations in its genome. Orf3a, an accessory protein encoded by the genome of SARS-CoV-2, plays a significant role in viral infection and pathogenesis. In the present in-silico study, 15,928 sequences of Orf3a reported worldwide were compared to identify variations in this protein. Our analysis revealed...

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PMID: 33527091
DOI: 10.1016/j.bbrep.2021.100933

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