Article
Chemerin reverses the malignant phenotype and induces differentiation of human hepatoma SMMC7721 cells.
Archives of pharmacal research - 1 Feb 2021
Li Ming, Sun Pengcheng, Dong Kaikai, Xin Ye, TaiLulu Aslee, Li Qinyu, Sun Jing, Peng Min, Shi Ping
Abstract excerpt
Chemerin exhibits an inhibitory effect on hepatocellular carcinoma; however, the underlying mechanism is unclear. Here, low chemerin expression was confirmed in samples of liver cancer patients and hepatoma cells. Chemerin altered hepatoma cell morphology but had no effect on normal hepatocytes. Chemerin inhibited proliferation of several human hepatoma cell lines. Real-time PCR detection of hepatocellular...
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