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Identification of differentially methylated genes as diagnostic and prognostic biomarkers of breast cancer

26 Jan 2021

Abstract excerpt

BACKGROUND: Aberrant DNA methylation is significantly associated with breast cancer. METHODS: In this study, we aimed to determine novel methylation biomarkers using a bioinformatics analysis approach that could have clinical value for breast cancer diagnosis and prognosis. Firstly, differentially methylated DNA patterns were detected in breast cancer samples by comparing publicly available datasets (GSE72245 and...

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PMID: 33499882
DOI: 10.1186/s12957-021-02124-6

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