Article
DNA Methylation Profiles of Tph1A and BDNF in Gut and Brain of L. Rhamnosus-Treated Zebrafish.
Biomolecules - 22 Jan 2021
Cuomo Mariella, Borrelli Luca, Della Monica Rosa, Coretti Lorena, De Riso Giulia, D'Angelo Lancellotti di Durazzo Luna, Fioretti Alessandro, Lembo Francesca, Dinan Timothy G, Cryan John F, Cocozza Sergio, Chiariotti Lorenzo
Abstract excerpt
The bidirectional microbiota-gut-brain axis has raised increasing interest over the past years in the context of health and disease, but there is a lack of information on molecular mechanisms underlying this connection. We hypothesized that change in microbiota composition may affect brain epigenetics leading to long-lasting effects on specific brain gene regulation. To test this hypothesis, we used Zebrafish...
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