Article
Association of PER2 gene single nucleotide polymorphisms with genetic susceptibility to systemic lupus erythematosus.
Lupus - 1 Apr 2021
Dan Yi-Lin, Zhao Chan-Na, Mao Yan-Mei, Wu Qian, He Yi-Sheng, Hu Yu-Qian, Xiang Kun, Yang Xiao-Ke, Sam Napoleon Bellua, Wu Guo-Cui, Pan Hai-Feng
Abstract excerpt
The circadian clock plays a crucial role in the progress of systemic lupus erythematosus (SLE). In this study, we performed a case-control study to explore the association between Period 2 (PER2) gene single nucleotide polymorphisms (SNPs) and the susceptibility of systemic lupus erythematosus (SLE). A total of 492 SLE patients and 493 healthy controls were included. The improved multiple ligase detection...
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